Recent Publications



  • Abraham, R.R., R.E. Pollitzer, M. Gokden and Goulden, P., Spontaneous pituitary apoplexy during the second trimester of pregnancy, with sensory loss. BMJ Case Rep, 2016.
  • Adler RA, Saag K, Weinstein RS: Glucocorticoid-Induced Osteoporosis. In Marcus R, Feldman D, Nelsen DA, Rosen CJ (eds) Osteoporosis 4th edition, Elsevier-Academic Press, San Diego, CA 2016.
  • Brito JP, Schilz S, Singh Ospina NM, Rodriguez-Gutierrez R, Maraka S, Sangaralingham L, Montori V. Antithyroid Drugs- the most common treatment for Graves’ disease in the United States: a nationwide population-based study. Thyroid. 2016 Aug;26(8):1144-5.
  • Delivanis DA, Erickson D, Atwell TD, Natt N, Maraka S, Grant SD, Eiken PW, Nathan MA, Young WF Jr, Bancos I. Procedural and clinical outcomes of percutaneous adrenal biopsy in a high risk population for adrenal malignancy. Clin Endocrinol (Oxf). 2016 Nov;85(5):710-716.
  • Eguchi A, Lazic M, Armando AM, Phillips SA, Katebian R, Maraka S, Quehenberger O, Sears DD, Feldstein AE. Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress. J Mol Med (Berl). 2016 Nov;94(11):1241-1253.
  • Fujiwara T, Zhou J, Ye S, Zhao H. RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival. Cell Death Dis. 7:e2300, 2016. PMCID: PMC4973353.
  • Fujiwara T, Ye S, Castro-Gomes T, Winchell CG, Andrews NW, Voth D, Varughese KI, Mackintosh SG, Feng Y, Pavlos N, Nakamura T, Manolagas SC, Zhao H. PLEKHM1-DEF8-RAB7 complex regulates lysosome positioning and bone homeostasis. JCI Insight. 1(17):e86330, 2016. PMCID: PMC5070964.
  • Fujiwara Y, Piemontese M, Liu Y, Thostenson JD, Xiong J, O’Brien CA. RANKL (Receptor Activator of NFκB Ligand) Produced by Osteocytes Is Required for the Increase in B Cells and Bone Loss Caused by Estrogen Deficiency in Mice. J Biol Chem. 2016 Nov 25;291(48):24838-24850. PMID: 27733688.
  • Iyer S, Han L, Ambrogini E, Yavropoulou M, Fowlkes J, Manolagas SC, Almeida M. Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes. J Bone Miner Res, 10.1002/jbmr.2934. Epub ahead of print. Aug 4, 2016. PMID: 27491024
  • Jilka RL, O’Brien CA. The Role of Osteocytes in Age-Related Bone Loss. Curr Osteoporos Rep. 2016 Feb;14(1):16-25. doi: 10.1007/s11914-016-0297-0. PMID: 26909563.
  • Jilka RL. The road to reproducibility in animal research. J Bone Miner Res. (2016) 31:1317-1319.
  • Liu Y, Almeida M, Weinstein RS, O’Brien CA, Manolagas SC, Jilka RL. Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice. Am J Physiol Endocrinol Metab. 2016 May 1;310(9):E762-73. doi: 10.1152/ajpendo.00501.2015. PMID: 26956187.
  • Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS. Impact of sarA and phenol-soluble modulins in the pathogenesis of osteomyelitis in diverse clinical isolates of Staphylococcus aureus. Infect Immun. 84:2586-2594, 2016. PMCID: PMC4995912.
  • Maraka S, Singh Ospina NM, O’Keeffe DT, Rodriguez-Gutierrez R, Espinosa De Ycaza AE, Wi CI, Juhn YJ, Coddington CC 3rd, Montori VM. Effects of increasing levothyroxine on pregnancy outcomes in women with uncontrolled hypothyroidism. Clin Endocrinol (Oxf). 2016 Aug 3. [Epub ahead of print].
  • Maraka S, Singh Ospina N, O’Keeffe DT, Rodriguez-Gutierrez R, Espinosa De Ycaza A, Wi CI, Juhn YJ, Coddington III CC, Montori VM, Stan MN. Effects of Levothyroxine Therapy on Pregnancy Outcomes in Women with Subclinical Hypothyroidism. Thyroid. 2016 Jul;26(7):980-6.
  • Maraka S, Kearns AE, Kittah NEN, O’Keeffe DT. Recurrent Euglycemic Diabetic Ketoacidosis after Discontinuation of Sodium-Glucose Cotransporter 2 Inhibitor. Diabetes Research and Clinical Practice. 2016 Aug;118:77-8.
  • Maraka S, Singh Ospina NM, O’Keeffe DT, Espinosa De Ycaza A, Gionfriddo MR, Erwin P, Coddington C, Stan MN, Murad MH, Montori VM. Subclinical Hypothyroidism in Pregnancy: A Systematic Review and Meta-analysis. Thyroid. 2016 Apr;26(4):580-90.
  • McElfish PA, Goulden PA, Bursac Z, Hudson J, Purvis RS, Kim Yeary KH, Aitaoto N, Kohler PO. Engagement practices that join scientific methods with community wisdom: designing a patient-centered, randomized control trial with a Pacific Islander community. Nurs Inq. 2016 Jun 20. Doi: 10.1111/nin.12141. [Epub ahead of print]. PMID: 27325179
  • McElfish PA, Moore R, Woodring DW, Purvis R, Maskarinec GG, Bing WI, Hudson J, Kohler PO, Goulden PA. Social ecology and diabetes self-management among Pacific Islanders in Arkansas. J Fam Med Dis Prev. 2016 Mar;2(1):026.
  • O’Keeffe DT, Maraka S, Rizza R. HbA1c in the Evaluation of Diabetes Mellitus. JAMA. 2016 Feb; 315(6):605-6 PERSPECTIVE
  • O’ Keeffe DT, Maraka S. Blood pressure lowering for cardiovascular disease. Lancet. 2016 Jul 9;388(10040):125. LETTER
  • Piemontese M, Xiong J, Fujiwara Y, Thostenson JD, O’Brien CA. Cortical bone loss caused by glucocorticoid excess requires RANKL production by osteocytes and is associated with reduced OPG expression in mice. Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E587-93. doi: 10.1152/ajpendo.00219.2016. PMID: 27460899.
  • Piemontese M, Onal M, Xiong J, Han L, Thostenson JD, Almeida M, O’Brien CA. Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage. Sci Rep. 2016 Apr 11;6:24262. doi: 10.1038/srep24262. PubMed PMID: 27064143; PubMed Central PMCID: PMC4827128.
  • Rodriguez-Gutierrez R, Gionfriddo MR, Singh Ospina NM, Maraka S, Tamhane S, Montori VM, Brito JP. Shared Decision Making in Endocrinology-Present and Future Directions. Lancet Diabetes Endocrinol. 2016 Aug;4(8):706-16.
  • Rodriguez-Gutierrez R, Maraka S, Singh Ospina NM, Montori V, Brito JP. Levothyroxine overuse: time for an about face? The Lancet Diabetes & Endocrinology. 2016 Oct 28. [Epub ahead of print]
  • Ruiz P, Martin-Millan M, Gonzalez-Martin MC, Almeida M, González Macias J, Ros MA. 2016. CathepsinKCre mediated deletion of βcatenin results in dramatic loss of bone mass by targeting both osteoclasts and osteoblastic cells. Scientific Reports 6:36201.
  • Singh Ospina NM, Maraka S, Montori VM, Thompson GB, Young WF Jr. Clinical Question: When and how should patients with multiple endocrine neoplasia type 1 be screened for thymic and bronchial carcinoid tumors? Clinical Endocrinology. 2016 Jan;84(1):13-6.
  • Singh Ospina NM, Maraka S, Espinosa De Ycaza A, O’Keeffe D, Brito JP, Gionfriddo MR, Castro MR, Morris JC, Erwin P, Montori VM. Diagnostic accuracy of thyroid nodule growth to predict malignancy in thyroid nodules with benign cytology: Systematic review and meta-analysis. Clinical Endocrinology. 2016 Jul;85(1):122-31.
  • Singh Ospina N, Maraka S, Espinosa De Ycaza AE, Ahn HS, Castro MR, Morris JC, Montori VM, Brito JP. Physical exam in asymptomatic people drivers the detection of thyroid nodules undergoing ultrasound guided fine needle aspiration biopsy. Endocrine. 2016 Nov;54(2):433-439.
  • Singh Ospina N, Maraka S, Rodriguez-Gutierrez R, Espinosa de Ycaza AE, Jasim S, Gionfriddo M, Castaneda-Guarderas A, Brito JP, Al Nofal A, Erwin P, Wermers R, Montori V. Comparative efficacy of parathyroidectomy and active surveillance in patients with mild primary hyperparathyroidism: a systematic review and meta-analysis. Osteoporos Int. 2016 Aug 25. [Epub ahead of print]
  • Singh Ospina NM, Brito JP, Maraka S, Espinosa De Ycaza A, Rodriguez-Gutierrez R, Gionfriddo MR, Castaneda-Guarderas A, Benkhadra K, Al Nofal A, Erwin P, Morris JC, Castro MR, Montori VM. Diagnostic accuracy of ultrasound guided fine needle aspiration biopsy for thyroid malignancy: systematic review and meta-analysis. Endocrine 2016 Sep;53(3):651-61.
  • Singh Ospina NM, Rodriguez-Gutierrez R, Maraka S, Espinosa De Ycaza A, Jasim S, Castaneda-Guarderas A, Gionfriddo MR, Al Nofal A, Brito JP Erwin P, Richards M, Wermers R, Montori VM. Outcomes of Parathyroidectomy in Patients with Primary Hyperparathyroidism: A Systematic Review and Meta-analysis. World J Surg. 2016 Oct;40(10):2359-77.
  • Singh Ospina N, Maraka S, Espinosa de Ycaza AE, Brito JP, Castro MR, Morris JC, Montori VM. Prognosis of patients with benign thyroid nodules: a population-based study. Endocrine. 2016 Oct;54(1):148-155.
  • Ucer S, Iyer S, Kim HN, Han L, Rutlen C, Allison K, Thostenson JD, de Cabo R, Jilka RL, O’Brien C, Almeida M, Manolagas SC. The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct. J Bone Miner Res. 10.1002/jbmr.3014. Epub ahead of print. Oct 7, 2016. PMID: 27714847
  • Weinstein RS: Chapter 247: Osteomalacia and Rickets. In Goldman L, Arend WP and Schafer AI (eds) Cecil Textbook of Medicine 25th Edition. Saunders, Philadelphia, PA 2016.
  • Ye S, Fujiwara T, Zhou J, Varughese KI, Zhao H. LIS1 regulates osteoclastogenesis through modulation of M-SCF and RANKL signaling pathways and CDC42. Int J Biol Sci. 12:1488-1499, 2016.
  • Yeary K, Aitaoto N. Goulden PA, McElfish PA, Developing a diabetes self-management education curriculum using community-based participatory research in a Pacific Islander community. Submitted to: Progress in Community Health Partnerships: Research, Education, and Action.
  • Yu Liu, Almeida M, Weinstein RS, O’Brien CA, Manolagas SC, Jilka RL. Skeletal Inflammation and Attenuation of Wnt Signaling, Wnt Ligand Expression and Bone Formation in Atherosclerotic ApoE Null Mice. Am J Physiol Endocrinol Metab, 10.1152/ajpendo.00501.2015. Epub ahead of print. Mar 8, 2016. PMID: 26956187
  • Zhu M, Sun BH, Saar K, Simpson C, Troiano N, Dallas SL, Tiede-Lewis LM, Nevius E, Pereira JP, Weinstein RS, Tommasini SM, Insogna KL. Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number and a Reduced Number of Osteoblasts In Vivo. J Bone Miner Res 31:864-873, 2016.



  • Commentary: ATP: The crucial component of secretory vesicles: Accelerated ATP/insulin exocytosis and prediabetes. Duvoor C, Dendi VS, Marco A, Shekhawat NS, Chada A, Ravilla R, Musham CK, Mirza W, Chaudhury A. Front Physiol. 2017 Feb 2;8:53. doi: 10.3389/fphys.2017.00053. eCollection 2017. No abstract available. PMID:28210227
  • Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management. Chaudhury A, Duvoor C, Reddy Dendi VS, Kraleti S, Chada A, Ravilla R, Marco A, Shekhawat NS, Montales MT, Kuriakose K, Sasapu A, Beebe A, Patil N, Musham CK, Lohani GP, Mirza W. Front Endocrinol (Lausanne). 2017 Jan 24;8:6. doi: 10.3389/fendo.2017.00006. eCollection 2017. Review. PMID:28167928
  • A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis. Garcia-Saenz-de-Sicilia M, Duvoor C, Altamirano J, Chavez-Araujo R, Prado V, de Lourdes Candolo-Martinelli A, Holanda-Almeida P, Becerra-Martins-de-Oliveira B, Fernandez-de-Almeida S, Bataller R, Caballeria J, Duarte-Rojo A. Am J Gastroenterol. 2017 Feb;112(2):306-315. doi: 10.1038/ajg.2016.539. Epub 2016 Dec 6. PMID:27922027
  • A rare benign intrathoracic mass in a patient with history of rocket explosion. Klair JS, Duvoor C, Meena N. Respir Med Case Rep. 2014 Nov 20;14:4-6. doi: 10.1016/j.rmcr.2014.11.003. eCollection 2015. PMID:26029565
  • Murad MH, Hasan R, Firwana B. Reply. J Vasc Surg. 2016 Jul; 64(1):265. PMID: 27345514.
  • Wang Z, Hasan R, Firwana B, Elraiyah T, Tsapas A, Prokop L, Mills JL, Murad MH. A systematic review and meta-analysis of tests to predict wound healing in diabetic foot. J Vasc Surg. 2016 Feb; 63(2 Suppl):29S-36S.e1-2. PMID: 26804365.
  • Elraiyah T, Prutsky G, Domecq JP, Tsapas A, Nabhan M, Frykberg RG, Firwana B, Hasan R, Prokop LJ, Murad MH. A systematic review and meta-analysis of off-loading methods for diabetic foot ulcers. J Vasc Surg. 2016 Feb; 63(2 Suppl):59S-68S.e1-2. PMID: 26804369.
  • Elraiyah T, Tsapas A, Prutsky G, Domecq JP, Hasan R, Firwana B, Nabhan M, Prokop L, Hingorani A, Claus PL, Steinkraus LW, Murad MH. A systematic review and meta-analysis of adjunctive therapies in diabetic foot ulcers. J Vasc Surg. 2016 Feb; 63(2 Suppl):46S-58S.e1-2. PMID: 26804368.
  • Hasan R, Firwana B, Elraiyah T, Domecq JP, Prutsky G, Nabhan M, Prokop LJ, Henke P, Tsapas A, Montori VM, Murad MH. A systematic review and meta-analysis of glycemic control for the prevention of diabetic foot syndrome. J Vasc Surg. 2016 Feb; 63(2 Suppl):22S-28S.e1-2. PMID: 26804364.
  • Elraiyah T, Domecq JP, Prutsky G, Tsapas A, Nabhan M, Frykberg RG, Hasan R, Firwana B, Prokop LJ, Murad MH. A systematic review and meta-analysis of débridement methods for chronic diabetic foot ulcers. J Vasc Surg. 2016 Feb; 63(2 Suppl):37S-45S.e1-2. PMID: 26804366.
  • Firwana B, Sonbol MB, Diab M, Raza S, Hasan R, Yousef I, Zarzour A, Garipalli A, Doll D, Murad MH, Al-Kali A. Tyrosine kinase inhibitors as a first-line treatment in patients with newly diagnosed chronic myeloid leukemia in chronic phase: A mixed-treatment comparison. Int J Cancer. 2016 Mar 15; 138(6):1545-53. PMID: 26455714.
  • Ferwana M, Abdulmajeed I, Alhajiahmed A, Madani W, Firwana B, Hasan R, Altayar O, Limburg PJ, Murad MH, Knawy B. Accuracy of urea breath test in Helicobacter pylori infection: meta-analysis. World J Gastroenterol. 2015 Jan 28; 21(4):1305-14. PMID: 25632206; PMCID: PMC4306177.