Calendar Year: 2016

  1. Arthur, JM, E. Elnagar and N Karakala. Biomarkers of Glomerular Diseases. In: Biomarkers of Kidney Disease. Ed. C.L. Edelstein. Elsevier. 2016.
  2. Bose C, Shah SV, Karaduta OK, Kaushal GP. Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury. PLoS One. 11(12): e0165576, 2016. PMCID: PMC5156412
  3. Herzog C, Haun RS, Shah SV, Kaushal GP. Proteolytic processing and inactivation of MCP-1 by meprins. Biochem Biophysics Reports 8:146-150, 2016. (available in ScienceDirect).
  4. Kaushal GP, Shah SV. Autophagy in Acute Kidney Injury. Invited review, Kidney International 89: 779-791, 2016. PMCID: PMC4801755
  5. Raju I, Kaushal GP, and Haun RS. Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer. Biol Chem 397(11):1135-1146, 2016.
  6. Wolf BJ, Spainhour JC, Arthur JM, Janech MG, Petri M, Oates JC. Arthritis Rheumatol. 2016 Aug; 68(8):1955-63. PMID 26867033.

Calendar Year: 2015

  1. Alge JL, Arthur JM. Biomarkers of AKI: a review of mechanistic relevance and potential therapeutic implications. Clin J Am Soc Nephrol. 2015 Jan 7;10(1):147-55. Review. PMID: 25092601. PMCID: PMC4284423
  2. Bose C, Megyesi JK, Shah SV, Hiatt KM, Hall KA, Karaduta O, Swaminathan S. Evidence suggesting a role of iron in a mouse model of nephrogenic systemic fibrosis. PLoS One. 2015 Aug 25;10(8):e0136563. PMID: 26305890. PMCID: PMC4549214
  3. Chandrika BB, Yang C, Ou Y, Feng X, Muhoza D, Holmes AF, Theus S, Deshmukh S, Haun RS, Kaushal GP. Endoplasmic reticulum stress-induced autophagy provides cytoprotection from chemical hypoxia and oxidant injury and ameliorates renal ischemia-reperfusion injury. PLoS One. 2015 Oct 7;10(10):e0140025. PMID: 26444017. PMCID: PMC4596863
  4. Dupre TV, Doll MA, Shah PP, Sharp CN, Kiefer A, Scherzer MT, Saurabh K, Saforo D, Siow D, Casson L, Arteel GE, Jenson AB, Megyesi J, Schnellmann RG, Beverly LJ, Siskind LJ. Suramin protects from cisplatin-induced acute kidney injury. Am J Physiol Renal Physiol. 2016 Feb 1;310(3):F248-58. PMID: 26661653
  5. Easom, A. Overview of CKD for the APRN: APRN role in CKD, stages 4 to 5, not on dialysis. Core curriculum for Nephrology Nursing: Module 6. The APRN’s approaches to care in nephrology (6th ed., pp. 19-52). (2015) Ed. Caroline Counts. Pitman, NJ: American Nephrology Nurses’ Association.
  6. Ghaffar U, Easom AK. A quality improvement project: Strategies to reduce intradialytic hypotension in hemodialysis patients. Nephrol News Issues. 2015 May;29(5):30, 32, 34 passim. PMID: 26197697
  7. Herzog C, Marisiddaiah R, Haun RS, Kaushal GP. Basement membrane protein nidogen-1 is a target of meprin β in cisplatin nephrotoxicity. Toxicol Lett. 2015 Jul 16;236(2):110-6. PMID: 25957482. PMCID: PMC4457671
  8. Hobeika L, Hunt KJ, Neely BA, Arthur JM. Comparison of the rate of renal function decline in non-proteinuric patients with and without diabetes. Am J Med Sci. 2015 Dec;350(6):447-52. PMID: 26624901
  9. Janech MG, Rodgers JL, Arthur JM, Velez JC. Letter to the editor: “Concern regarding quantification of urinary nephrin by a commercially available ELISA”. Am J Physiol Renal Physiol. 2015 Aug 1;309(3):F269-70. No abstract available. PMID: 26357486
  10. Koyner JL, Davison DL, Brasha-Mitchell E, Chalikonda DM, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Bennett MR, Kimmel PL, Seneff MG, Chawla LS. Furosemide stress test and biomarkers for the prediction of AKI severity. J Am Soc Nephrol. 2015 Aug;26(8):2023-31. PMID: 25655065. PMCID: PMC4520172 [Available on 2016-08-01]
  11. Megyesi J, Tarcsafalvi A, Li S, Hodeify R, Seng NS, Portilla D, Price PM. Increased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis. Am J Physiol Renal Physiol. 2015 Jan 15;308(2):F122-30. PMID: 25428126. PMCID: PMC4340262
  12. Neely BA, Ferrante JA, Chaves JM, Soper JL, Almeida JS, Arthur JM, Gulland FM, Janech MG. Proteomic analysis of plasma from California sea lions (Zalophus californianus) reveals apolipoprotein E as a candidate biomarker of chronic domoic acid toxicosis. PLoS One. 2015 Apr 28;10(4):e0123295. PMID: 25919366. PMCID: PMC4412824
  13. Neely BA, Soper JL, Gulland FM, Bell PD, Kindy M, Arthur JM, Janech MG. Proteomic analysis of cerebrospinal fluid in California sea lions (Zalophus californianus) with domoic acid toxicosis identifies proteins associated with neurodegeneration. Proteomics. 2015 Dec;15(23-24):4051-63. PMID: 26364553
  14. Shah SV, Shukla AM, Bose C, Basnakian AG, Rajapurkar M. Recent advances in understanding the pathogenesis of atherosclerosis in CKD patients. J Ren Nutr. 2015 Mar;25(2):205-8. Review. PMID: 25556310
  15. Shukla AM, Bose C, Karaduta OK, Apostolov EO, Kaushal GP, Fahmi T, Segal MS, Shah SV. Impact of hydroxychloroquine on atherosclerosis and vascular stiffness in the presence of chronic kidney disease. PLoS One. 2015 Sep 28;10(9):e0139226. PMID: 26414017. PMCID: PMC4586379
  16. Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP. Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med. 2015 Sep;86:90-101. PMID: 26025579. PMCID: PMC4554811 [Available on 2016-09-01]
  17. Subathra M, Korrapati M, Howell LA, Arthur JM, Shayman JA, Schnellmann RG, Siskind LJ. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015 Aug 1;309(3):F204-15. PMID: 26041445. PMCID: PMC4525094 [Available on 2016-08-01]
  18. Syed F, Mena-Gutierrez A, Ghaffar U. A case of iced-tea nephropathy. N Engl J Med. 2015 Apr 2;372(14):1377-8. PMID: 25830441
  19. Velez JC, Kadian M, Taburyanskaya M, Bohm NM, Delay TA, Karakala N, Rockey DC, Nietert PJ, Goodwin AJ, Whelan TP. Hepatorenal acute kidney injury and the importance of raising mean arterial pressure. Nephron. 2015;131(3):191-201. PMID: 26485256. PMCID: PMC4655825 [Available on 2016-10-21]
  20. Whitaker RM, Stallons LJ, Kneff JE, Alge JL, Harmon JL, Rahn JJ, Arthur JM, Beeson CC, Chan SL, Schnellmann RG. Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury. Kidney Int. 2015 Dec;88(6):1336-1344. PMID: 26287315. PMCID: PMC4675682 [Available on 2016-06-01]


Akrawinthawong K, Shaw MK, Kachner J, Apostolov EO, Basnakian AG,·Shah S,·Tilak J, McCullough PA. Urine catalytic iron and neutrophil gelatinase-associated lipocalin as companion early markers of acute kidney injury after cardiac surgery: A prospective pilot study. Cardiorenal Med 3:7-16, 2013.

Apostolov EP, Basnakian AG, Ok E, Shah SV. Carbamylated low-density lipoprotein: Nontraditional risk factor for cardiovascular events in patients with chronic kidney disease. J Ren Nutr 2012; 22(1):134-138.

Baliga R, Rajapurkar M, Shah SV. Catalytic (labile) iron in kidney disease. In: Kopple and Massry’s Nutritional Management of Renal Disease, 3rd edition. Joel D. Kopple and Shaul G. Massry, eds. Elsevier Inc., San Diego, Ch. 6, pp. 93-104, 2013.

Capolongo G. Abul-Ezz S. Moe OW. Sakhaee K. Subclinical celiac disease and crystal-induced kidney disease following kidney transplant. American Journal of Kidney Diseases. 60(4):662-7, 2012 Oct.

Castano AP., Chau BN., Xin C., Hartner J., Ren S., Linn G., Li J., Tran PT., Kaimal V., Huang X., Chang AN., Li S., Kalra A., Grafals M., Portilla D., Mackenna DA., Orkin SH., Duffield JS. MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways. Sci Transl Med 2012 4(121):121ra18.

Cerda J., Chawla LS., Faubel S., Cruz DN., Dong Z., Goldstein SL., Humphreys BD., Koyner JL., Jaber BL., Liu KD., Nolin TD., Polu KR., Portilla D., Rys-Sikora KE., Okusa MD., Shaffer RN. AKI transition of care: a potential opportunity to detect and prevent CKD. Clin J Am Soc Nephrol 2013 March; 8(3):476-83.

Choi HY, Moon SJ, Ratliff BB, Ahn SH, Jung A, Lee M, Lee S, Lim BJ, Kim BS, Plotkin M, Ha SK,Park HC. Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury. Plos One, Feb 4;9(2)e87853, 2014.

Herzog C, Yang C, Holmes A, Kaushal GP. zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function. Am J Physiol Renal Physiol 2012 Oct; 303(8):F1239-50.

Herzog C, Haun RS, Ludwig A, Shah SV and Kaushal GP. ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A. J Biol Chem. 2014 May 9;289(19):13308-22.

Hodeify R, Tarcsafalvi A, Megyesi J, Safirstein RL, and Price PM. Cdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicity. Am J Physiol Renal Physiol 2011; 300: F1171-F1179.

Hodeify R and Price PM. The end of the beginning: a possible mechanism of renal cell death after ischemia/reperfusion. Kidney Int 2012; 81: 720-721.

Hossam M, Tarcsafalvi A, Megyesi J, Hodeify R, Price PM. Sexual dimorphism of ER stress-induced kidney injury. J Am Soc Nephrol 2011; 22: 372A.

Hodeify R, Megyesi J, Tarcsafalvi A, Mustafa HI, Hti Lar Seng NS, Price PM. 2013. Gender differences control the susceptibility to ER stress-induced acute kidney injury. Am J Physiol Renal Physiol 304: F875-F882. PMCID: PMC3625845.

Jesinkey SR, Funk JA, Stallons LJ, Wills LP, Megyesi JK, Beeson CC, and Schnellmann RG. 2014. Formoterol Restores Mitochondrial and Renal Function after Ischemia-Reperfusion Injury. J Am Soc Nephrol. 25: 1157-1162.

Kaushal GP., Shah SV. Kidney-liver dialogue in acute kidney injury. Am J Physiol Renal Physiol 2012 Dec; 303(11):F1503-4.

Kaushal GP. Autophagy protects proximal tubular cells from injury and apoptosis. Kidney Int 2012 Dec; 82(12):1250-3.

Kaushal GP., Haun RS., Herzog C., Shah SV. Meprin A metalloproteinase and its role in acute kidney injury. Am J Physiol Renal Physiol 2013 May; 304(9):F1150-8.

Kaushal GP., Shah SV. Letter to: Kidney Int. 83(3):531. 2013 Mar. Non-apoptotic effects of antiapoptotic agent zVAD-fmk in renal injury.

Kaushal V, Herzog C, Haun RS, Kaushal GP. Caspase protocols in mice. Methods Mol Biol. 2014; 1133:141-154.

Kaushal GP, Shah SV: Challenges and Advances in the Treatment of Acute Kidney Injury. J Am Soc Nephrol 25:877-883, 2014.

Kaushal GP, Elbein A, Carver WE. The Extracellular Matrix. Book chapter in “Medical Biochemistry”, 4th Edition (Baynes, J and Dominiczak, M Eds), Chapter 29, pp. 380-392.Elsevier Mosby Inc., 2014.

Krause MW, Fonseca VA, Shah SV. Combination inhibition of the renin-angiotensin system: is more better? Kidney Int 2011; 80(3):245-55.

Krause MW, Shah SV. Chronic Kidney Disease (Updated). Monograph for online British Medical Journal, 2010-present(ongoing annual update).

Li S., Nagothu K., Ranganathan G., Ali SM., Shank B., Gokden N., Ayyadevara S., Megyesi J., Olivecrona G., Chugh SS., Kersten S., Portilla D. Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury. Am J Physiol Renal Physiol 2012 (303):F437-F448.

Krause MW, Alam M. Peritoneal Dialysis Solutions, UptoDate, annual update, 2013.

Krause MW, Shah SV. Chronic kidney disease (Updated) [Internet]. BMJ Point of Care / Best Practice; [cited 2014 May 2].

Lee D, Shenoy S, Nigatu Y, Plotkin M. Id proteins regulate capillary repair and perivascular cell proliferation following ischemia-reperfusion injury. Plos One, 2014 Feb 7;9(2):e88417.

Li S, Mariappan N, Megyesi J, Shank B, Kannan K, Theus S, Kaushal GP, Price PM, Duffield JS, Portilla D. 2013. Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction. Am J Physiol Renal Physiol 305: F618-F627.

Megyesi J, Tarcsafalvi A, Safirstein RL, Price PM. Dependence of renal fibrosis on a cell cycle regulator. J Am Soc Nephrol 2011; 22: 756A.

Molitoris BA, Okusa MD, Palevsky PM, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Faubel SG, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings. Clin J Am Soc Nephrol 2012; 7(5):856-60.

Okusa MD, Molitoris BA, Palevsky PM, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Faubel S, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: a report from an NIDDK workshop–prevention trials. Clin J Am Soc Nephrol 2012; 7(5):851-5.

Pandey R, Kochar R, Kemp S, Rotaru D, Shah SV “Ehrlichiosis presenting with toxic shock-like syndrome and hemophagocytic lymphohistiocytosis” – J Ark Med Soc. 2013 Jun;109(13):280-2.

Parikh CR, Shaw AD, Go AS, Faubel SG, Kellum JA, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene T, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol 2012; 7(5):844-50.

Price P, Hodeify R. 2012. The End of the Beginning: a Possible Mechanism of Renal Cell Death after Ischemia/reperfusion. Kidney Int 81: 720-721. PMCID: PMC3324283.

Rajapurkar MM, Shah SV, Lele SS, Hegde UN, Lensing SY, Gohel K, Mukhopadhyay B, Gang S, Eigenbrodt ML. Association of catalytic iron with cardiovascular disease. Am J Cardiol 2012; 109(3):438-42.

Rajapurkar MM, Hegde U, Bhattacharya A, Alam MG, Shah SV. Effect of deferiprone, an oral iron chelator, in diabetic and non-diabetic glomerular disease. Toxicol Mech Methods 23(1):5-10, 2013. PMID:22978744.

Rajapurkar M, Baliga R, Shah SV. Catalytic (labile) iron in kidney disease. In: Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, 5th ed., Alpern RJ, Moe OW, Caplan M, editors. Elsevier Inc., San Diego, Ch. 89, pp. 3007-3020, 2013.

Rajapurkar MM, Lele SS, Malavade TS, Kansara MR, Hegde UN, Gohel KD, Gang SD, Shah SV, Mukhopadhyay BN Serum catalytic iron: A novel biomarker for coronary artery disease in patients on maintenance hemodialysis. Indian J Nephrol. 2013 Sep;23(5):332-7.

Ramani VC, Kaushal GP, Haun RS. Proteolytic action of kallikrein-related peptidase 7 produces unique active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains. Biochim Biophys Acta 2011; 1813(8):1525-31.

Safirstein RL, Megyesi J, Tarcsafalvi A, Hodeify R, Price PM. 2011. STAT3 activation via tyrosine phosphorylation is cytoreductive during cisplatin-induced acute kidney injury. J.Am.Soc.Nephrol 2011;22: 620A.

Sethi S, Pothineni N, Syal G, Ali S, Krause MW. Aortic Intimal Sarcoma Masquerading as Bilateral Renal Artery Stenosis. J Nephrology 2013;26(5):941-44

Shah SV, Fonseca VA. Iron and diabetes revisited. Diabetes Care 2011; 34(7):1676-7.

Shah SV, Rajapurkar MM, Baliga R. The role of catalytic iron in acute kidney injury. Clin J Am Soc Nephrol 2011; 6(10):2329-31.

Swaminathan S, Shah SV. Novel inflammatory mechanisms of accelerated atherosclerosis in kidney disease. Kidney Int 2011; 80(5):453-63.

Swaminathan S, Bose C, Shah SV, Hall KA, Hiatt KM.Gadolinium contrast agent-induced CD163+ ferroportin+ osteogenic cells in nephrogenic systemic fibrosis. Am J Pathol. 2013 Sep;183(3):796-807.

Wang Z, Herzog C, Kaushal GP, Gokden N, Mayeux PR. Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis. Shock 35 2011; (2):141-7

Wang Z, Shah SV, Liu H, Baliga R. Role of cytochrome P450 2E1 and its interrelationship with transcription factor Nrf2 in myoglobinuric acute kidney injury. Kidney Int advance online publication 9 April 2014; doi: 10.1038/ki.2014.65.