Calendar Year: 2017

  1. Abdallah AO, Kaur V, Mahmoud F, & Motwani, P. 2017. Image Diagnosis: Splenic Infarction Associated with Oral Contraceptive Pills in a Healthy Young Woman. The Permanente Journal, 21. PMID: 28488992
  2. Atiq MO, Ravilla R, Kumar A, Haider S, Ji-Ling T, Arnaoutakis K, Motwani P, Siegel E, Sasapu A, Mahmoud F, Harrington SE. Aggressive care at the end of life: A study of practice based factors in patients with stage IV cancer. Journal of Clinical Oncology 2017 35:8_suppl, 80-80
  3.  Atwal D, Joshi KP, Ravilla R, Mahmoud F. Pembrolizumab-Induced Pancytopenia: A Case Report. Perm J. 2017; 21. PMID: 28746020. PMCID: PMC5528855
  4.  Atwal D, Joshi KP, Jeffus S, Ntambi J, Mahmoud F. Well-Differentiated Neuroendocrine Tumor-A Low b-Grade Tumor’s Aggressive Course and Dismal Outcome: A Case Report. Perm J. 2017; 21. PMID: 28633725. PMCID: PMC5478591
  5. Chesney J, Awasthi S, Curti B, Hutchins L, Linette G, Triozzi P, Tan MCB, Brown RE, Nemunaitis J, Whitman E, Windham C, Lutzky J, Downey GF, Batty N, Amatruda T. Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB–IVM1c melanoma. Melanoma Res. 2017 Nov 22. PMID: 29176501
  6. Devan R, Motwani P, Harrington S, Wilson LA, Bowers, S, Hutchins, L and Makhoul, I. Arkansas’ Adult Sickle Cell Clinical Program. J Ark Med Soc. 2017 September;114 (3):64.
  7. Firwana B, Avaritt N, Shields B, Ravilla R., Makhoul I, Hutchins L & Mahmoud F. Do checkpoint inhibitors rely on gut microbiota to fight cancer? J Onc Pharm Pract. 2017. PMID: 28625074. DOI: 1078155217715903.
  8. Govindarajan, R, and ER Siegel. The Effect of Exposure to Thiazolidinediones on the Development of Head-and-Neck Cancer in Patients with Diabetes Mellitus. Translational Research in Oral Oncology. 2017;2:1-5. DOI: 10.1177/2057178X17739809.
  9. Griffin RJ, Dings RPM and Makhoul I. Further rationale for optimal combined modality treatments. Oncotarget. 2017 Apr 18;8(16):25831-25832. PMID: 28415727
  10. Kaur V, Swami A, Alapat D, Abdallah AO, Motwani P, Hutchins LF, Jethava Y. Clinical Characteristics, molecular profile and outcomes of myeloid sarcoma: a single institution experience over 13 years. Hematology. 2018 Jan; 23(1):17-24. Epub 2017 Jun 2. PMID: 28574302
  11. Hao L, Mahmoud F. Image Diagnosis: A striking bleomycin-induced skin toxicity: Flagellate hyperpigmentation. Perm J. 2017;21. PMID: 28080950. PMCID: PMC5224796
  12. Hutchins LF, Makhoul I, Emanuel PD, Pennisi A, Siegel ER, Jousheghany F, Guo X, Pashov AD, Monzavi-Karbassi B, Kieber-Emmons T. Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects. 2017 Oct 23;8(58):99161-99178. eCollection 2017 Nov 17. PMID: 29228761
  13. Jeffus SK, Gardner JM, Steliga MA, Shah AA, Stelow EB, Arnaoutakis K. Hyalinizing Clear Cell Carcinoma of the Lung: Case Report and Review of the Literature. Am J Clin Pathol. 2017 Jul 1;148(1):73-80. PMID: 28927164
  14. Johnsrud J, Abdallah AO, Schichman SA, Xiang Z. Image Diagnosis: Zinc-Induced Copper Deficiency Causing Pancytopenia Recognized on Bone Marrow Examination. 2017;21:16-077. PMID: 2821910. PMICD: PMC5283791
  15. Kieber-Emmons T, Makhoul I, Pennisi A, Siegel ER, Emanuel PD, Monzavi-Karbassi B, Steplewski Z, Beck JT, Hutchins LF. Managing Expectations in the Transition to Proof of Concept Studies. Rev Recent Clin Trials. 2017;12(2):111-123. PMID: 28325150
  16. Mahmoud F, Wilkinson JT, Gizinski A, Viswamitra S, Gokden N, Vander Schilden J. Could knee inflammatory synovitis be induced by pembrolizumab? J Oncol Pharm Pract. 2017 Jan 1:1078155217701292. PMID: 28355971
  17. Mahmoud F, Shields B, Makhoul I, Avaritt N, Wong HK, Hutchins LF, Shalin S, Tackett AJ. Immune Surveillance in Melanoma: From immune attack to melanoma escape and even counterattack. Cancer Biol Ther. 2017 July 1;18(7):451-496. PMID: 28513269. PMCID: PMC5639850
  18. Makhoul I, Todorova VK, Siegel ER, Erickson SW, Dhakal I, Raj VR, Lee JY, Orloff MS, Griffin RJ, Henry-Tillman RS, Klimberg S, Hutchins LF and Kadlubar SA. Germline Genetic Variants in ANGPT1, ANGPT2 and FGF2 are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients. PLoS One. 2017 Jan 3;12(1):e0168550. PMID: 28045923. PMCID: PMC5207665
  19. Makhoul I. The Microbiota, Cancer and the “Human Superorganism”. J Ark Med Soc. 2017 June;113(12):282.
  20. Makhoul I. The Seventh Rule. J Ark Med Soc. December;114 (8):126. No abstract available
  21. Makhoul I, Pennisi A, Maraboyina S, and Bryant-Smith G: Neoadjuvant Chemotherapy and Radiation Therapy. In: The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th edition, edited by Kirby Bland, Edward Copeland, Suzanne Klimberg, and William Gradishar. Philadelphia: Elsevier, 2018
  22. Makhoul I: Treatment Strategies in Breast Cancer. In: The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th edition, edited by Kirby Bland, Edward Copeland, Suzanne Klimberg, and William Gradishar. Philadelphia: Elsevier, 2018
  23. Makhoul I., Banderudrappagari R. and Pennisi A. Follow-Up Care and Rehabilitation of the Breast Cancer Patient: General Considerations for Follow-Up. In: The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th edition, edited by Kirby Bland, Edward Copeland, Suzanne Klimberg, and William Gradishar. Philadelphia: Elsevier, 2018
  24. Makhoul, I., Atrash, S., Arnaoutakis, K., Safar, M., Pennisi, A., Huffman, L. and Griffin, R. Therapeutic Implications of Angiogenesis in Cancer in Biochemical Basis and Therapeutic Implications of Angiogenesis; Springer, 2017.
  25. Mooradian MJ, Piotrowska Z, Drapkin B, Dias-Santagata D, Marcoux N, Arnaoutakis K, Nagy, Lanman, Iafrate J, Farago A, Mino-Kenudsen M, Hata A, Sequist LV. Clonal Evolution and the Role of Serial Liquid Biopsies in a Case of Small-Cell Lung Cancer-Transformed EGFR Mutant Non-Small-Cell Cancer. JCO Precision Oncology. 2017. DOI: 10.1200/PO.17.00123
  26. Nima ZA, Alwbari AM, Dantuluri V, Hamzah RN, Sra N, Motwani P, Arnaoutakis K, Levy RA, Bohliqa AF, Nedosekin D, Zharov VP, Makhoul I, Biris AS. Targeting nano drug delivery to cancer cells using tunable, multi-layer, silver-decorated gold nanorods. J Appl Toxicol. 2017 Dec;37(12):1370-1378. PMID: 28730725
  27.  Sasapu A, Guru Murthy GS, Insuasti-Beltran G, Makhoul I. Large Granular Lymphocytic Leukemia and Cocaine Abuse in A Patient with Chronic Neutropenia – Are They Co-Existing or Causally Related? J Hematol Thromb. 2017;3(1): 2.
  28. Shah N, Clair J, Makhoul I. Abdominal Compartment Syndrome: Condition Necessitating Prompt Management. Ark Med Soc. 2017 January;113(7):138.
  29. Shields BD, Mahmoud F, Taylor EM, Byrum SD, Sengupta D, Koss B, Baldini G, Ransom S, Cline K, Mackintosh SG, Edmondson RD, Shalin S, Tackett AJ. Indicators of responsiveness to immune checkpoint inhibitors. Sci Rep. 2017 Apr 11;7(1):807. PMID: 28400597. PMCID: PMC5429745
  30. Sonbol MB, Firwana B, Wang Z, Ahn DH, Borad MJ, Makhoul I, Ramanathan RK and Bekaii-Saab, TS. Second-line treatment in patients with pancreatic ductal adenocarcinoma: A meta-analysis. Journal of Clinical Oncology. 2017;35:15_suppl, e15779-e15779. PMID: 28817187
  31. Todorova VK, Makhoul I, Dhakal I, Wei J, Stone A, Carter W, Owen A, Klimberg VS. Polymorphic Variations Associated with Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients. Oncol Res. 2017 Sep 21;25(8):1223-1229. PMID: 28256194
  32. Todorova VKMakhoul I, Wei J, Klimberg VS. Circulating miRNA Profiles of Doxorubicin-induced Cardiotoxicity in Breast Cancer Patients. Ann Clin Lab Sci. 2017 Mar;47(2):115-119. PMID: 28442511
  33. Yu LR, Cao Z, Makhoul I, Daniels JR, Klimberg S, Wei JY, Bai JP, Li J, Lathrop JT, Beger RD, Todorova VK. Immune response proteins as predictive biomarkers of doxorubicin-induced cardiotoxicity in breast cancer patients. Exo Biol Med (Maywood). 2017 Jan 1. PMID: 29224368

Calendar Year: 2016

  1. Atrash S, Makhoul I, Mizell JS, Hutchins L, Mahmoud F. Response of metastatic mucosal melanoma to immunotherapy: It can get worse before it gets better. J Oncol Pharm Pract. 2016 Jan 24. [Epub ahead of print]. PMID: 26811403
  2. Bansal M, Abdallah AO, Pennisi A, Arnaoutakis K, Makhoul I, Mehta P. Improving communication on intent of chemotherapy using QOPI scores and PDSA cycles. J Cancer Educ. 2016 Dec;31(4):736-741. PMID: 27929800.
  3. Coleman HN, Greenfield WW, Stratton SL, Vaughn R, Kieber A, Moerman-Herzog AM, Spencer HJ, Hitt WC, Quick CM, Hutchins LF, Mackintosh SG, Edmondson RD, Erickson SW, Nakagawa M. Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination. Cancer Immunol Immunother. 2016 May;65(5):563-73. Epub 2016 Mar 15. PMID: 26980480
  4. Firwana B, Ravilla R, Raval M, Hutchins L, Mahmoud F. Sarcoidosis-like syndrome and lymphadenopathy due to checkpoint inhibitors. J Oncol Pharm Pract. 2016 Sep 2. [Epub ahead of print]. PMID: 27590328
  5. Govindarajan R, Posey J, Chao CY, Lu R, Jadhav T, Javed AY, Javed A, Mahmoud FA, Osarogiagbon RU, Manne U. A comparison of 12-gene colon cancer assay gene expression in African American and Caucasian patients with stage II colon cancer. BMC Cancer. 2016 Jun 18;16:368. PMID: 27316467. PMCID: PMC4912774
  6. Govindarajan R, Gujja S, Siegel ER, Batra A, Saeed A, Lai K, James JD, Fogel BJ, Williamson S. Programmed cell death-ligand 1 (PD-L1) expression in anal cancer. Am J Clin Oncol. 2016 Nov 15. [Epub ahead of print] PMID: 27849650
  7. Kaur V , Haider S, Sasapu A, Mehta P, Arnaoutakis K , Makhoul I. Addressing Opioid-Associated Constipation Using Quality Oncology Practice Initiative Scores and Plan-Do-Study-Act Cycles. DOI: 10.1200/JOP.2016.013797; published online on October 4, 2016 before print
  8. Kieber-Emmons T, Monzavi-Karbassi B, Hutchins LF, Pennisi A, Makhoul I. Harnessing benefit from targeting tumor associated carbohydrate antigens. Hum Vaccin Immunother. 2016 Dec. 8:0. [epub ahead of pring]. PMID: 27929800
  9. Klair JS, Girotra M, Hutchins LF, Caradine KD, Aduli F, Garcia-Saenz-de-Sicilia M. Ipilimumab-induced gastrointestinal toxicities: A management algorithm. Dig Dis Sci. 2016 Feb 5 [Epub ahead of print] PMID: 26846115
  10. Mahmoud F, Shields B, Makhoul I, Hutchins LF, Shalin SC, Tackett, AJ. Role of ezh2 histone methyltrasferase in melanoma progression and metastasis. Cancer Biol Ther. 2016 Apr 22:0 [Epub ahead of print] PMID: 27105109
  11. Makhoul I, Montgomery CO, Gaddy D, Suva LJ. The best of both worlds-managing the cancer, saving the bone. Nat Rev Endocrinol 2016 Jan;12(1):29-42. Epub 2015 Oct 27. PMID: 26503674
  12. Mahmoud F, Abdallah AO, Arnaoutakis K, Makhoul I. Metastatic Renal Cell Carcinoma Presenting as Painful Chewing Successfully Treated with Combined Nivolumab and Sunitinib. Perm J 2016 Jun 27;20(3) [Epub ahead of print]. PMID: 27352410
  13. Makhoul I. Health care disparity and the pursuit of happiness. J Ark Med Soc. 2016 Jun; 112(15):268. PMID: 2743497
  14. Makhoul I, Motwani P, Schafer L, Arnaoutakis K, Mahmoud F, Safar M, Graves D, Mehta P, Govindarajan R, Hutchins L and Carol Thrush. Integrating Collaborative Learning and Competition in a Hematology/Oncology Training Program. J Cancer Educ. 2016 Aug 12. [Epub ahead of print]. PMID: 27516202
  15. Makhoul I. Cancer heterogeneity, patient diversity and next-generation cognitive computing. J Ark Med Soc. 2016 December;113(14):126.
  16. Makhoul I, Yacoub A and Siegel E. Type 2 Diabetes Mellitus is Associated with Increased Risk of Pancreatic Cancer: A Veteran Administration Registry Study. (SAGE Open Medicine, 2016).
  17. Monzavi-Karbassi B, Siegel ER, Medarametla S, Makhoul I, Kieber-Emmons T. Breast cancer survival disparity between Afican American and Caucasian women in Arkansas: A race-by-grade analysis. Oncol Lett. 2016 Aug;12(2):1337-1342 Epub 2016 Jun 29. PMID: 27446434. PMCID: PMC4950488
  18. Monzavi-Karbassi B, Gentry R, Kaur V, Siegel ER, Jousheghany F, Medarametla S, Fuhrman BJ, Safar AM, Hutchins LF, Kieber-Emmons T. Pre-diagnosis blood glucose and prognosis in women with breast cancer. Cancer metab. 2016 Apr 6;4:7. PMID: 27054036. PMCID: PMC4822279
  19. Pennisi A, Kieber-Emmons T, Makhoul I, Hutchins L. Relevance of pathological complete response after neoadjuvant therapy for breast cancer. Breast Cancer: Basic and Clin Res 2016:10 103-106. PMID: 27478380 PMCID: PMC4961053
  20. Romano RC, Gardner JM, Shalin SC, Ram R, Govindarajan R, Montgomery CO, Gilley JH, Nicholas RW. High relative expression of Pannexin 3 (PANX3) in an axillary sweat gland carcinoma with osteosarcomatous transformation. Am J Dermatopathol 2016 Jul 6. [Epub ahead of print] PMID: 27391460
  21. Todorova VK, Makhoul I, Siegel ER, Wei J, Stone A, Carter W, Beggs ML, Owen A, Klimberg VS. PloS One. 2016 Aug 4;11(8):e0160224. PMID: 27490685 PMCID: PMC4973957